Seminars relevant to Informatics

[Ekaterina Churkina <Ekaterina.Churkina AT ed.ac.uk>]

Biomedical AI Seminar series

 

Multiple Sclerosis Disease Measurement in the modern era

 

When: 11 November, 11am

Where: G.07, Informatics Forum

 

Register here: Multiple Sclerosis Disease Measurement in the modern era Tickets, Wednesday, November 11  •  11 AM - 12:30 PM | Eventbrite

 

Abstract:

Multiple Sclerosis remains the most common cause of disability in young adults. It is a highly developed therapeutic area, with numerous approved therapies. The most effective of these (so-called highly effective therapies, HET) almost completely control neuro-inflammation and its clinical correlate, MS relapses. Chronic gradual disability progression continues despite neuro-inflammation control with HET, and this progression is complex to measure and predict. Efficient drug development, targeting this residual unmet need that drives poor outcomes in people living with MS, depends on innovation in both the measurement and prediction of disability. Contemporary MS measurement, both in clinical trials and in clinical practice, presents a challenge and an opportunity, and the lecture will explore related ideas and themes.

 

Speaker:

James Overell is a neurologist and senior medical leader at Roche, based in Basel, Switzerland, with extensive experience in multiple sclerosis (MS), neuro-immunology and clinical drug development.

James joined Roche in 2019 as Principal Global Medical Director within the Multiple Sclerosis/Neuro-inflammation Group, before moving to Clinical Development in 2021 to lead clinical development programmes in neuro-immunology. His work at Roche has focused particularly on progressive MS, innovative approaches to disease monitoring and the development of new therapies for neuro-immunological disorders.

Prior to joining Roche, James was a Consultant Neurologist at the Institute of Neurological Sciences in Glasgow, where he specialised in MS and inflammatory neurological disorders. From 2012 to 2019, he led the Glasgow MS Clinical Research Centre, directing numerous clinical trials and observational studies of disease-modifying and neuroprotective therapies for MS.

James graduated with distinction from Edinburgh Medical School and holds an MSc in Clinical Pharmacology and an MD. He was awarded an Honorary Clinical Associate Professorship by the University of Glasgow in 2019.

 

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336. Is e buidheann carthannais a th’ ann an Oilthigh Dhùn Èideann, clàraichte an Alba, àireamh clàraidh SC005336.